If the coefficients of $$x$$ and $$x^{2}$$ in the expansion of $$(1+x)^{\mathrm{p}}(1-x)^{\mathrm{q}}, \mathrm{p}, \mathrm{q} \leq 15$$, are $$-3$$ and $$-5$$ respectively, then the coefficient of $$x^{3}$$ is equal to _____________.

If the maximum value of the term independent of $$t$$ in the expansion of $$\left(\mathrm{t}^{2} x^{\frac{1}{5}}+\frac{(1-x)^{\frac{1}{10}}}{\mathrm{t}}\right)^{15}, x \geqslant 0$$, is $$\mathrm{K}$$, then $$8 \mathrm{~K}$$ is equal to ____________.

Let the coefficients of x^{$$-$$1} and x^{$$-$$3} in the expansion of $${\left( {2{x^{{1 \over 5}}} - {1 \over {{x^{{1 \over 5}}}}}} \right)^{15}},x > 0$$, be m and n respectively. If r is a positive integer such that $$m{n^2} = {}^{15}{C_r}\,.\,{2^r}$$, then the value of r is equal to __________.

The number of positive integers k such that the constant term in the binomial expansion of $${\left( {2{x^3} + {3 \over {{x^k}}}} \right)^{12}}$$, x $$\ne$$ 0 is 2^{8} . l, where l is an odd integer, is ______________.