Given below are two statements : one is labelled as Assertion A and the other is labelled as Reason R.

Assertion A : In recombinant DNA technology, lysozyme is used for disrupting bacterial cells while cellulase is for plant cells.

Reason R : Isolation of genetic material needs disruption of cells.

In the light of the above statements, choose the most appropriate answer from the options given below :

$$ \text { Match List-I with List-II. } $$

Choose the correct answer from the options given below:

Given below are two statements :

Statement I : Plasmids are autonomously replicating DNA.

Statement II: Plasmids are extrachromosomal DNA.

In the light of the above statements, choose the most appropriate answer from the options given below:

During PCR, primers bind to the DNA strands in the $\_\_\_\_$ step.