Cell Cycle and Cell Division · Biology · NEET

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MCQ (Single Correct Answer)

1

Given below are two statements :

Statement I : Chromosomes are fully condensed at the end of prophase I.

Statement II : Meiosis I resembles mitosis.

In the light of the above statements, choose the most appropriate answer from the options given below :

RE-NEET 2026
2

The correct sequence of adult cell cycle phases is $\_\_\_\_$ .

RE-NEET 2026
3

$$ \text { Match List I with List II : } $$

List-I
(Phase of cell cycle)
List-II
(Activity)
A. $\mathrm{G}_1$ phase I. Actual cell division occurs
B. S phase II. Cell is metabolically active and continuously grows but does not replicate its DNA
C. $\mathrm{G}_2$ Phase III. Synthesis of DNA occurs and the amount of DNA per cell doubles
D. M phase IV. Proteins are synthesized while cell growth continues

Choose the correct answer from the options given below :

NEET 2026
4

What is the main function of the spindle fibers during mitosis?

NEET 2025
5

Given below are two statements:

Statement I: Failure of segregation of chromatids during cell cycle resulting in the gain or loss of whole set of chromosome in an organism is known as aneuploidy.

Statement II: Failure of cytokinesis after anaphase stage of cell division results in the gain or loss of a chromosome is called polyploidy.

In the light of the above statements, choose the correct answer from the options given below:

NEET 2024 (Re-Examination)
6

Recombination between homologous chromosomes is completed by the end of

NEET 2024 (Re-Examination)
7

Match List-I with List-II :

List - I List - II
(A) Metacentric chromosome (I) Chromosome has a terminal centromere
(B) Sub-metacentric chromosome (II) Middle centromere forming two equal arms of chromosome
(C) Acrocentric chromosome (III) Centromere is slightly away from the middle of chromosome resulting into two unequal arms
(D) Telocentric chromosome (IV) Centromere is situated close to its end forming one extremely short and one very long arm

Choose the correct answer from the options given below:

NEET 2024 (Re-Examination)
8

Match List-I with List-II.

List - I
Event
List - II
Stage of Prophase-I (Meiosis-I)
(A) Chiasmata formation (I) Pachytene
(B) Crossing over (II) Diakinesis
(C) Synaptonemal complex formation (III) Diplotene
(D) Terminalisation of chiasmata (IV) Zygotene

Choose the correct answer from the options given below :

NEET 2024 (Re-Examination)
9

Match List-I with List-II.

List - I List - II
(A) Cells are metabolically active and proliferate (I) G$$_2$$ phase
(B) DNA replication takes place (II) G$$_1$$ phase
(C) Proteins are synthesised (III) G$$_0$$ phase
(D) Quiescent stage with metabolically active cells (IV) S phase

Choose the correct answer from the options given below:

NEET 2024 (Re-Examination)
10

Spindle fibers attach to kinetochores of chromosomes during

NEET 2024
11

Given below are two statements:

Statement I : Chromosomes become gradually visible under light microscope during leptotene stage.

Statement II : The beginning of diplotene stage is recognized by dissolution of synaptonemal complex.

In the light of the above statements, choose the correct answer from the options given below:

NEET 2024
12

Following are the stages of cell division :

A. Gap 2 phase

B. Cytokinesis

C. Synthesis phase

D. Karyokinesis

E. Gap 1 phase

Choose the correct sequence of stages from the options given below :

NEET 2024
13

Match List I with List II :

List - I
(Sub Phases of Prophase I)
List - II
(Specific Characters)
A. Diakinesis I. Synaptonemal complex formation
B. Pachytene II. Completion of terminalisation of chiasmata
C. Zygotene III. Chromosomes look like thin threads
D. Leptotene IV. Appearance of recombination nodules

Choose the correct answer from the options given below

NEET 2024
14

The dissolution of synaptonemal complex occurs during :

NEET 2023 Manipur
15

Doubling of the number of chromosomes can be achieved by disrupting mitotic cell division soon after :

NEET 2023 Manipur
16

During which stages of mitosis and meiosis, respectively does the centromere of each chromosome split ?

NEET 2023 Manipur
17

Which one of the following is the quiescent stage of cell cycle?

NEET 2023 Manipur
18

Select correct sequence of substages of Prophase-I of Meiotic division :

(A) Zygotene

(B) Pachytene

(C) Diakinesis

(D) Leptotene

(E) Diplotene

Choose the correct answer from the options given below :

NEET 2023 Manipur
19

The process of appearance of recombination nodules occurs at which sub stage of prophase I in meiosis?

NEET 2023
20

Which of the following stages of meiosis involves division of centromere?

NEET 2023
21

Among eukaryotes, replication of DNA takes place in :

NEET 2023
22

Match List I with List II:

List I List II
(A) M Phase (I) Proteins are synthesized
(B) G$$_2$$ Phase (II) Inactive phase
(C) Quiescent stage (III) Interval between mitosis and initiation of DNA replication
(D) G$$_1$$ Phase (IV) Equational division

Choose the correct answer from the options given below :

NEET 2023
23

Select the correct statements.

A. Tetrad formation is seen during Leptotene.

B. During Anaphase, the centromeres split and chromatids separate.

C. Terminalization takes place during Pachytene.

D. Nucleolus, Golgi complex and ER are reformed during Telophase.

E. Crossing over takes place between sister chromatids of homologous chromosome.

Choose the correct answer from the options given below:

NEET 2023
24

Given below are two statements:

Statement I : During G0 phase of cell cycle, the cell is metabolically inactive.

Statement II : The centrosome undergoes duplication during S phase of interphase.

In the light of the above statements, choose the most appropriate answer from the options given below:

NEET 2023
25

Which stage of meiosis can last for months or years in the oocytes of some vertebrates?

NEET 2022 Phase 2
26

Identify the correct sequence of events during Prophase I of meiosis:

(a) Synapsis of homologous chromosomes

(b) Chromosomes become gradually visible under microscope

(c) Crossing over between non-sister chromatids of homologous chromosomes

(d) Terminalisation of chiasmata

(e) Dissolution of synaptonemal complex

Choose the correct answer from the options given below:

NEET 2022 Phase 2
27

Bivalent or Tetrad formation is a characteristic feature observed during

NEET 2022 Phase 2
28

With respect to metaphase, which of the following statements is incorrect?

NEET 2022 Phase 2
29

Which one of the following never occurs during mitotic cell division?

NEET 2022 Phase 1
30

The appearance of recombination nodules on homologous chromosomes during meiosis characterizes:

NEET 2022 Phase 1
31

Match List I with List II.

List - I List - II
(a) Metacentric chromosome (i) Centromere situated close to the end forming one extremely short and one very long arms
(b) Acrocentric chromosome (ii) Centromere at the terminal end
(c) Submetacentric (iii) Centromere in the middle forming two equal arms of chromosomes
(d) Telocentric chromosome (iv) Centromere slightly away from the middle forming one shorter arm and one longer arm

Choose the correct answer from the options given below:

NEET 2022 Phase 1
32

Regarding Meiosis, which of the statements is incorrect?

NEET 2022 Phase 1
33

Select the incorrect statement with reference to mitosis :

NEET 2022 Phase 1
34
Which of the following stages of meiosis involves division of centromere?
NEET 2021
35
Match List-I with List-II.

List-I List-II
(a) S phase (i) Proteins are synthesized
(b) $${G_2}$$ phase (ii) Inactive phase
(c) Quiescent stage (iii) Interval between mitosis and initiation of DNA replication
(d) $${G_1}$$ phase (iv) DNA replication


Choose the correct answer from the options given below.
NEET 2021
36
The fruit fly has 8 chromosomes (2n) in each cell. During interphase of Mitosis if the number of chromosomes at G1 phase is 8, what would be the number of chromosomes after S phase?
NEET 2021
37
Which stage of meiotic prophase shows terminalisation of chiasmata as its distinctive feature?
NEET 2021
38
The centriole undergoes duplication during :
NEET 2021
39
Some dividing cells exit the cell cycle and enter vegetative inactive stage. This is called quiescent stage (G0). This process occurs at the end of
NEET 2020 Phase 1
40
Match the following with respect to meiosis

(A) Zygotene      (i) Terminalization
(B) Pachytene     (ii) Chiasmata
(C) Diplotene      (iii) Crossing over
(D) Diakinesis     (iv) Synapsis

Select the correct option from the following
NEET 2020 Phase 1
41
Dissolution of the synaptonemal complex occurs during
NEET 2020 Phase 1
42
Identify the correct statement with regard to G1 phase (Gap 1) of interphase
NEET 2020 Phase 1
43
Cells in G0 phase :
NEET 2019
44
The correct sequence of phases of cell cycle is :
NEET 2019
45
The stage during which separation of the paired homologous chromosomes begins is
NEET 2018
46
Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cell. If APC is defective in a human cell, which of the following is expected to occur?
NEET 2017
47
Which of the following options gives the correct sequence of events during mitosis?
NEET 2017
48
During cell growth, DNA synthesis takes place on
NEET 2016 Phase 2
49
When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?
NEET 2016 Phase 2
50
Match the stages of meiosis in column I to their characteristic features in column II and select the correct option using the codes given below.

Column $${\rm I}$$ Column $${\rm I}$$$${\rm I}$$
A. Pachytene (i) Pairing of homologous
chromosomes
B. Metaphase $${\rm I}$$ (ii) Terminalisation of
chiasmata
C. Diakinesis (iii) Crossing-over takes
place
D. Zygotene (iv) Chromosomes align
at equatorial plate
NEET 2016 Phase 2
51
Which of the following is not a characteristic feature during mitosis in somatic cells?
NEET 2016 Phase 1
52
In meiosis crossing over is initiated at
NEET 2016 Phase 1
53
Spindle fibres attach on to
NEET 2016 Phase 1
54
Arrange the following events of meiosis in correct sequence
(i)  Crossing over
(ii)  Synapsis
(iii)  Terminalisation of chiasmata
(iv)  Disappearance of nucleolus
AIPMT 2015
55
Select the correct option.
Column $${\rm I}$$ Column $${\rm I}$$$${\rm I}$$
A. Synapsis aligns homologous (i) Anaphase $${\rm I}$$$${\rm I}$$
B. Synthesis of RNA and protein (ii) Zygotene
C. Action of enzymes recombinase (iii) G2-phase
D. Centromeres do not separate
but chromatids move towards
opposite poles
(iv) Anaphase $${\rm I}$$
(v) Pachytene
AIPMT 2015 Cancelled Paper
56
A somatic cell that has just completed the S phase of its cell cycle, as compared to gamete of the same species, has
AIPMT 2015 Cancelled Paper
57
During which phase(s) of cell cycle, amount of DNA in a cell remains at 4C level if the initial amount is denoted as 2C?
AIPMT 2014
58
The enzyme recombinase is required at which stage of meiosis?
AIPMT 2014
59
In 'S' phase of the cell cycle
AIPMT 2014
60
During meiosis I, the chromosomes start pairing at
NEET 2013 (Karnataka)
61
During the metaphase stage of mitosis, spindle fibres attach to chromosomes at
NEET 2013 (Karnataka)
62
A stage of mitosis is shown in the diagram.
Which stage is it and what are its characteristics? NEET 2013 (Karnataka) Biology - Cell Cycle and Cell Division Question 48 English
NEET 2013 (Karnataka)
63
The complex formed by a pair of synapsed homologous chromosomes is called
NEET 2013
64
A stage in cell division is shown in the figure. Select the answer which gives correct identification of the stage with its characteristics. NEET 2013 Biology - Cell Cycle and Cell Division Question 49 English
NEET 2013
65
Identify the meiotic stage in which the homologous chromosomes separate while the sister chromatids remain associated at their centromeres.
AIPMT 2012 Mains
66
Given below is the representation of a certain event at a particular stage of a type of cell division. Which is this stage? AIPMT 2012 Prelims Biology - Cell Cycle and Cell Division Question 43 English
AIPMT 2012 Prelims
67
During gamete formation, the enzyme recombinase participates during
AIPMT 2012 Prelims
68
At metaphase, chromosomes are attached to the spindle fibres by their
AIPMT 2011 Mains
69
Select the correct option with respect to mitosis.
AIPMT 2011 Prelims
70
During mitosis, ER and nucleolus begin to disappear at
AIPMT 2010 Prelims
71
Which stages of cell division do the following figures A and B represent respectively? AIPMT 2010 Prelims Biology - Cell Cycle and Cell Division Question 47 English
AIPMT 2010 Prelims
72
Given below is a schematic break-up of the phases/stages of cell cycle. Which one of the following is the correct indication of the stage/phase in the cell cycle?
AIPMT 2009 Biology - Cell Cycle and Cell Division Question 60 English
AIPMT 2009
73
Synapsis occurs between
AIPMT 2009
74
At what stage of the cell cycle are histone proteins synthesized in a eukaryotic cell?
AIPMT 2005
75
In the somatic cell cycle
AIPMT 2004
76
If you are provided with root-tips of onion in your class and are asked to count the chromosomes, which of the following stages can you most conveniently look into?
AIPMT 2004
77
Which one of the following precedes reformation of the nuclear envelope during M phase of the cell cycle?
AIPMT 2004
78
What is the reason of formation of embryoid from pollen grain in tissue culture medium ?
AIPMT 2002
79
If a diploid cell is treated with colchicine then it becomes : -
AIPMT 2002
80
Best material for the study of mitosis in laboratory is
AIPMT 2002
81
Mitotic spindle is mainly composed of which protein?
AIPMT 2002
82
Spindle fibre unite with which structure of chromosomes?
AIPMT 2000
83
In which stage of cell cycle, DNA replication occurs?
AIPMT 2000