Principles of Inheritance and Variation · Biology · NEET

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MCQ (Single Correct Answer)

1
A human female with Turner’s syndrome :
NEET 2014
2
Fruit colour in squash is an example of :
NEET 2014
3
A man whose father was colour blind marries a women who had a colour blind mother and normal father. What percentage of male children of this couple will be colour blind?
NEET 2014
4
A gene showing codominance has :
NEET 2015
5
A colour blind man marries a woman with normal sight who has no history of colour blindness in her family. What is the probability of their grandson being colour blind?
NEET 2015
6
A pleiotropic gene -
NEET 2015
7
In his classic experiments on pea plants, Mendel did not use :
NEET 2015
8
The term "linkage" was coined by -
NEET 2015
9
In the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. NEET 2015 Biology - Principles of Inheritance and Variation Question 148 English
NEET 2015
10

Given below are two statements:

Statement I: When many alleles of a single gene govern a character, it is called polygenic inheritance.

Statement II: In Polygenic inheritance, the effect of each allele is additive.

In the light of the above statements, choose the correct answer from the options given below.

NEET 2024 (Re-Examination)
11

Match List-I with List-II:

List - I
Type of Inheritance
List - II
Example
(A) Incomplete dominance (I) Blood groups in human
(B) Co-dominance (II) Flower colour in Antirrhinum
(C) Pleiotropy (III) Skin colour in human
(D) Polygenic inheritance (IV) Phenylketonuria

Choose the correct answer from the options given below:

NEET 2024 (Re-Examination)
12

When a tall pea plant with round seeds was selfed, it produced the progeny of :

(a) Tall plants with round seeds and

(b) Tall plants with wrinkled seeds.

Identify the genotype of the parent plant.

NEET 2024 (Re-Examination)
13

Aneuploidy is a chromosomal disorder where chromosome number is not the exact copy of its haploid set of chromosomes, due to :

A. Substitution

B. Addition

C. Deletion

D. Translocation

E. Inversion

Choose the most appropriate answer from the options given below :

NEET 2024 (Re-Examination)
14

The mother has $$\mathrm{A}+$$ blood group the father has $$\mathrm{B}+$$ and the child is $$\mathrm{A}+$$. What can be the possibility of genotypes of all three, respectively?

A. $$I^A I^A|I B i| I^B i$$

B. $$I^A I^A\left|I^B i\right| I^A i$$

C. $$I^B i\left|I^A I^A\right| I^A I^B$$

D. $$\left|A \beta^A\right| I^B I^B \mid I^A i$$

E. $$I^A i\left|I^B i\right| I^A i$$

Choose the correct answer from the option given below:

NEET 2024 (Re-Examination)
15

Which one of the following can be explained on the basis of Mendel's Law of Dominance?

A. Out of one pair of factors one is dominant and the other is recessive.

B. Alleles do not show any expression and both the characters appear as such in F$$_2$$ generation.

C. Factors occur in pairs in normal diploid plants.

D. The discrete unit controlling a particular character is called factor.

E. The expression of only one of the parental characters is found in a monohybrid cross.

Choose the correct answer from the options given below:

NEET 2024
16

A pink flowered Snapdragon plant was crossed with a red flowered Snapdragon plant. What type of phenotype/s is/are expected in the progeny?

NEET 2024
17

In a plant, black seed color $$(\mathrm{BB} / \mathrm{Bb})$$ is dominant over white seed color $$(\mathrm{bb})$$. In order to find out the genotype of the black seed plant, with which of the following genotype will you cross it?

NEET 2024
18

Match List I with List II

List - I List - II
A. Two or more alternative forms of a gene I. Back cross
B. Cross of F$$_1$$ progeny with homozygous recessive parent II. Ploidy
C. Cross of F$$_1$$ progeny with any of the parents III. Allele
D. Number of chromosome sets in plant IV. Test cross

Choose the correct answer from the options given below:

NEET 2024
19

As per ABO blood grouping system, the blood group of father is $$\mathrm{B}^{+}$$, mother is $$\mathrm{A}^{+}$$ and child is $$\mathrm{O}^{+}$$. Their respective genotype can be

A. IBi/IAi/ii

B. IBIB/IAIA/ii

C. iIB/iIA/IAIB

D. IAi/IBi/IAi

E. iIB/iIA/IAIB

Choose the most appropriate answer from the options given below :

NEET 2024
20

Match List - I with List - II.

List - I List - II
(A) Monohybrid Cross (I) 1 : 1
(B) Dihybrid Cross (II) 1 : 2 : 1
(C) Incomplete dominance (III) 3 : 1
(D) Test Cross (IV) 9 : 3 : 3 : 1

Choose the correct answer from the options given below :

NEET 2023 Manipur
21

A heterozygous pea plant with violet flowers was crossed with homozygous pea plant with white flower. Violet is dominant over white. Which one of the following represents the expected combinations among 40 progenies formed?

NEET 2023 Manipur
22

In which disorder change of single base pair in the gene for beta globin chain results in change of glutamic acid to valine ?

NEET 2023 Manipur
23

A certain plant homozygous for yellow seeds and red flowers was crossed with a plant homozygous for green seeds and white flowers. The F1 plants had yellow seeds and pink flowers. The F1 plants were selfed to get F2 progeny. Assuming independent assortment of the two characters, how many phenotypic categories are expected for these characters in the F2 generation ?

NEET 2023 Manipur
24

Select the correct statement/s with respect to mechanism of sex determination in Grasshopper.

(A) It is an example of female heterogamety.

(B) Male produces two different types of gametes either with or without X chromosome.

(C) Total number of chromosomes (autosomes and sex chromosomes) is same in both males and females.

(D) All eggs bear an additional X chromosome besides the autosomes.

Choose the correct answer from the options given below :

NEET 2023 Manipur
25

Frequency of recombination between gene pairs on same chromosome as a measure of the distance between genes to map their position on chromosome, was used for the first time by

NEET 2023
26

The phenomenon of pleiotropism refers to

NEET 2023
27

Which of the following statements are correct about Klinefelter’s Syndrome?

A. This disorder was first described by Langdon Down (1866).

B. Such an individual has overall masculine development. However, the feminine development is also expressed.

C. The affected individual is short statured.

D. Physical, psychomotor and mental development is retarded.

E. Such individuals are sterile.

Choose the correct answer from the options given below :

NEET 2023
28

Broad palm with single palm crease is visible in a person suffering from-

NEET 2023
29

Which one of the following symbols represents mating between relatives in human pedigree analysis?

NEET 2023
30

Given below are two statements:

Statement I : Sickle cell anaemia and haemophilia are autosomal dominant traits.

Statement II : Sickle cell anaemia and haemophilia are disorders of the blood.

In the light of the above statements, choose the correct answer from the options given below :

NEET 2022 Phase 2
31

In meiosis, crossing over and exchange of genetic material between homologous chromosomes are catalyzed by the enzyme

NEET 2022 Phase 2
32

The chromosomal theory of inheritance was proposed by

NEET 2022 Phase 2
33

What is the expected percentage of F2 progeny with yellow and inflated pod in dihybrid cross experiment involving pea plants with green coloured, inflated pod and yellow coloured constricted pod?

NEET 2022 Phase 2
34

If a female individual is with small round head, furrowed tongue, partially open mouth and broad palm with characteristic palm crease. Also the physical, psychomotor and mental development is retarded. The karyotype analysis of such an individual will show :

NEET 2022 Phase 2
35

Select the incorrect match regarding the symbols used in the Pedigree analysis:

NEET 2022 Phase 2
36

A normal girl, whose mother is haemophilic marries a male with no ancestral history of haemophilia. What will be the possible phenotypes of the offspring?

(a) Haemophilic son and haemophilic daughter.

(b) Haemophilic son and carrier daughter.

(c) Normal daughter and normal son.

(d) Normal son and haemophilic daughter.

Choose the most appropriate answer from the options given below:

NEET 2022 Phase 2
37

XO type of sex determination can be found in :

NEET 2022 Phase 1
38

Given below are two statements:

Statement I : Mendel studied seven pairs of contrasting traits in pea plants and proposed the Laws of Inheritance.

Statement II : Seven characters examined by Mendel in his experiment on pea plants were seed shape and colour, flower colour, pod shape and colour, flower position and stem height.

In the light of the above statements, choose the correct answer from the options given below :

NEET 2022 Phase 1
39

Which of the following occurs due to the presence of autosome linked dominant trait?

NEET 2022 Phase 1
40

Given below are two statements : one is labelled as Assertion (A) and the other is labelled as Reason (R).

Assertion (A) : Mendel's law of independent assortment does not hold good for the genes that are located closely on the same chromosome.

Reason (R) : Closely located genes assort independently.

In the light of the above statements, choose the correct answer from the options given below :

NEET 2022 Phase 1
41

If a colour blind female marries a man whose mother was also colour blind, what are the chances of her progeny having colour blindness?

NEET 2022 Phase 1
42

The recombination frequency between the genes a & c 5&, b & c is 15%, b & d is 9%, a & b is 20%, c & d is 25% and a & d is 29%. What will be the sequence of these genes on a linear chromosome?

NEET 2022 Phase 1
43
The production of gametes by the parents, formation of zygotes, the F1 and F2 plants, can be understood from a diagram called :
NEET 2021
44
Now-a-days it is possible to detect the mutated gene causing cancer by allowing radioactive probe to hybridise its complimentary DNA in a clone of cells, followed by its detection using autoradiography because:
NEET 2021
45
In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased?
NEET 2021
46
Experimental verification of the chromosomal theory of inheritance was done by
NEET 2020 Phase 1
47
Select the correct match
NEET 2020 Phase 1
48
How many true breeding pea plant varieties did Mendel select as pairs, which were similar except in one character with contrasting traits?
NEET 2020 Phase 1
49
In Antirrhinum (Snapdragon), a red flower was crossed with a white flower and in F1 generation, pink flowers were obtained. When pink flowers were selfed, the F2 generation showed white, red and pink flowers. Choose the incorrect statement from the following :
NEET 2019
50
The frequency of recombination between gene pairs on the same chromosome as a measure of the distance between genes was explained by :
NEET 2019
51
What is the genetic disorder in which an individual has an overall masculine development, gynaecomastia, and is sterile?
NEET 2019
52
What map unit (Centimorgan) is adopted in the construction of genetic maps?
NEET 2019
53
A gene locus has two alleles A, a. If the frequency of dominant allele A is 0.4, then what will be the frequency of homozygous dominant, heterozygous and homozygous recessive individuals in the population?
NEET 2019
54
Select the incorrect statement.
NEET 2019
55
Which of the following characteristics represent 'Inheritance of blood groups' in humans?
a. Dominance
b. Co-dominance
c. Multiple allele
d. Incomplete dominance
e. Polygenic inheritance
NEET 2018
56
Which of the following pairs is wrongly matched?
NEET 2018
57
A woman has an X-linked condition on one of her X chromosomes. This chromosome can be inherited by
NEET 2018
58
The genotypes of a Husband and Wife are IAIB and IAi.
Among the blood types of their children, how many different genotypes and phenotypes are possible?
NEET 2017
59
Which one from those given below is the period for Mendel’s hybridisation experiments ?
NEET 2017
60
A disease caused by an autosomal primary non-disjunction is :
NEET 2017
61
Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement.
NEET 2017
62
Among the following characters, which one was not considered by Mendel in his experiments on pea?
NEET 2017
63
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is
NEET 2016 Phase 2
64
The mechanism that causes a gene to move from one linkage group to another is called
NEET 2016 Phase 2
65
Pick out the correct statements :
(a) Haemophilia is a sex-linked recessive disease.
(b) Down's syndrome is due to aneuploidy.
(c) Phenylketonuria is an autosomal recessive gene disorder.
(d) Sickle cell anaemia is an X – linked recessive gene disorder.
NEET 2016 Phase 1
66
A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is contaning more number of chromosomes as compared to other dividing cells. This would results in -
NEET 2016 Phase 1
67
Match the terms in Column-I with their description in Column-II and choose the correct option :
Column-I Column-II
(a) Dominance (i) Many genes govern a single character
(b) Codominance (ii) In a heterozygous organism only one allele expresses
itself
(c) Pleiotropy (iii) In a heterozygous organism both alleles express
themselves fully
(d) Polygenic inheritance (iv) A single gene influences many characters
NEET 2016 Phase 1
68
Which of the following most appropriately describes haemophilia ?
NEET 2016 Phase 1
69
In a testcross involving F1 dihybrid flies, more parental-type offspring were produced than the recombinant-typeoffspring. This indicates
NEET 2016 Phase 1
70
A tall true breeding garden pea plant is crossed with a dwarf true breeding garden pea plant. When the F1 plants were selfed the resulting genotypes were in the ratio of -
NEET 2016 Phase 1
71
Multiple alleles are present
AIPMT 2015 Cancelled Paper
72
How many pairs of contrasting characters in pea plants were studied by Mendel in his experiments?
AIPMT 2015 Cancelled Paper
73
A man with blood group ‘A’ marries a woman with blood group ‘B’. What are all the possible blood groups of their offsprings?
AIPMT 2015 Cancelled Paper
74
Alleles are
AIPMT 2015 Cancelled Paper
75
The movement of a gene from one linkage group to another is called
AIPMT 2015 Cancelled Paper
76
An abnormal human baby with ‘XXX’ sex chromosomes was born due to
AIPMT 2015 Cancelled Paper
77
Down's syndrome in humans is due to :
NEET 2013 (Karnataka)
78
Which one is the incorrect statement with regards to the importance of pedigree analysis?
NEET 2013 (Karnataka)
79
If two persons with 'AB' blood group marry and have sufficiently large number of children, these children could be classified as 'A' blood group : 'AB' blood group : 'B' blood group in 1 : 2 : 1 ratio. Modern technique of protein electrophoresis reveals presence of both 'A' and 'B' type proteins in 'AB' blood group individuals. This is an example of :
NEET 2013
80
Select the incorrect statement with regard to Haemophilia is :
NEET 2013
81
Which idea is depicted by a cross in which the F1 generation resembles both the parents?
NEET 2013
82
Which of the following cannot be detected in a developing foetus by amniocentesis ?
NEET 2013
83
If both parents are carriers for thalessemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child ?
NEET 2013
84
A test cross is carried out to :
AIPMT 2012 Mains
85
Represented below is the inheritance pattern of the certain type of traits in humans. Which one of the following conditions could be an example of this pattern ? AIPMT 2012 Mains Biology - Principles of Inheritance and Variation Question 134 English
AIPMT 2012 Mains
86
Which one of the following is a wrong statement regarding mutations ?
AIPMT 2012 Mains
87
F2 generation in a Mendelian cross showed that both genotypic and phenotypic ratios are same as 1 : 2 : 1. It represents a case of
AIPMT 2012 Prelims
88
A normal - visioned man whose father was colour bilind, marries a woman whose father was also colour - blind. They have their first child as a daughter. What are the chances that this child would be colour blind
AIPMT 2012 Prelims
89
Which one of the following conditions of the zygotic cell would lead to the birth of a normal human female child ?
AIPMT 2011 Mains
90
Test cross in plants or in Drosophila involves crossing :
AIPMT 2011 Mains
91
Mutations can be induced with :
AIPMT 2011 Prelims
92
Which one of the following conditions correctly describes the manner of determining the sex ?
AIPMT 2011 Prelims
93
When two unrelated individuals or lines are crossed, the per romance of F1 hybrid is often superior to both parents. This phenomenon is called :
AIPMT 2011 Prelims
94
Study the pedigree chart of a certain family given below and select the correct conculusion which can be drawn for the character – AIPMT 2010 Mains Biology - Principles of Inheritance and Variation Question 122 English
AIPMT 2010 Mains
95
In antirrhinum two plants with pink flowers were hybridized. The F1 plants produced red, pink and white flowers in the proportion of 1 red, 2 pink and 1 white. What could be the genotype of the two plants used for hybridization ? Red flower colour is determined by RR, and White by rr genes -
AIPMT 2010 Mains
96
A cross in which an organism showing a dominant phenotype in crossed with the recessive parent in order to know its genotype is called -
AIPMT 2010 Mains
97
ABO blood grouping is controlled by gene I which has three alleles and show co-dominance. There are six genotypes. How many phenotypes in all are possible -
AIPMT 2010 Mains
98
ABO blood groups in humans are controlled by the gene I. It has three alleles – IA, IB and i. Since there are three different alleles, six different genotypes are possible. How many phenotypes can occur –
AIPMT 2010 Prelims
99
Select the correct statement from the ones given below with respect to dihybrid cross –
AIPMT 2010 Prelims
100
Which one of the following symbols and its representation, used in human pedigree analysis is correct –
AIPMT 2010 Prelims
101
The genotype of a plant showing the dominant phenotype can be determined by –
AIPMT 2010 Prelims
102
Which one of the following cannot be explained on the basis of Mendel's Law of Dominance?
AIPMT 2010 Prelims
103
Study the pedigree chart given below : AIPMT 2009 Biology - Principles of Inheritance and Variation Question 115 English What does it show ?
AIPMT 2009
104
The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC, because "O" in it refers to having :
AIPMT 2009
105
The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by
AIPMT 2009
106
Sickle-cell anemia is :
AIPMT 2009
107
Select the incorrect statement from the following :
AIPMT 2009
108
Which one of the following conditions in humans is correctly matched with its chromosomal abnormality/linkage?
AIPMT 2008
109
Haploids are more suitable for mutation studies than the diploids. This is because:
AIPMT 2008
110
Inheritance of skin colour in humans is an example of:-
AIPMT 2007
111
In the hexaploid wheat, the haploid(n) and basic(x) numbers of chromosomes are :
AIPMT 2007
112
A common test to find the genotype of a hybrid is by:-
AIPMT 2007
113
In pea plants, yellow seeds are dominant to green. If a heterozygous yellow seeded plant is crossed with a green seeded plant, what ratio of yellow and green seeded plants would you expect in F1 generation ?
AIPMT 2007
114
A human male produces sperms with the genotypes AB, Ab, AB, and ab pertaining to two diallelic characters in equal proportions. What is the corresponding genotype of this person ?
AIPMT 2007
115
Phenotype of an organism is the result of-
AIPMT 2006
116
Which one of the following is an example of polygenic inheritance ?
AIPMT 2006
117
How many different kinds of gametes will be produced by a plant having the genotype AABbCC ?
AIPMT 2006
118
Sickle cell anaemia has not been eliminated from the African population because-
AIPMT 2006
119
In Mendel's experiments with garden pea, round seed shape (RR) was dominant over wrinkled seeds (rr), yellow cotyledon (YY) was dominant over green cotyledon (yy). What are the expected phenotypes in the F2 generation of the cross RRYY × rryy ?
AIPMT 2006
120
Cri-du-chat syndrome in humans is caused by the-
AIPMT 2006
121
If a colour blind woman marries a normal visioned man, their sons will be
AIPMT 2006
122
Both sickle cell anemia and Huntington's chorea are-
AIPMT 2006
123
Test cross involves-
AIPMT 2006
124
G-6-P dehydrogenase deficiency is associated with haemolysis of -
AIPMT 2005
125
A women with 47 chromosomes due to three copies of chromosome 21 is characterized by
AIPMT 2005
126
A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children (2 daughter and 5 sons). Three of the sons suffer from the given disease but none of the daughters are affected. Which of the following mode of inheritance do you suggest for this disease
AIPMT 2005
127
In order to find out the different types of gametes produced by a pea plants having the genotype AaBb, it should be crossed to a plant with the genotype -
AIPMT 2005
128
A women with 47 chromosomes due to three copies of chromosome 21 is characterized by -
AIPMT 2005
129
Haemophilia is more commonly seen in human males than in human females because -
AIPMT 2005
130
A woman with normal vision, but whose father was colour bind, marries a colour blind man. Suppose that the fourth child of this couple was a boy. This boy -
AIPMT 2005
131
Which of the following is not a hereditary disease ?
AIPMT 2005
132
In a plant, red fruit (R) is dominant over yellow fruit (r) and tallness (T) is dominant over shortness (t). If a plant with RRTt genotype is crossed with a plant that is rrtt
AIPMT 2004
133
One of the parents of a cross has a mutation in its mitochondria. In that cross, that parent is taken as a male. During segregation of F2 progenies that mutation is found in -
AIPMT 2004
134
Lack of independent assortment of two genes A and B in fruit fly Drosophila is due to :-
AIPMT 2004
135
A male human is heterozygous for autosomal genes A and B and is also hemizygous for hemophilic gene h. What proportion of his sperms will be abh :-
AIPMT 2004
136
A normal woman, whose father was colour-blind is married to a normal man. The sons would be :-
AIPMT 2004
137
The recessive genes located on X-chromosomes in humans are always-
AIPMT 2004
138
The genes controlling the seven pea characters studied by Mendel are now known to be located on how many different chromosomes ?
AIPMT 2003
139
In Drosophila, the sex is determined by : -
AIPMT 2003
140
Pattern baldness, moustaches and beard in human males are examples of : -
AIPMT 2003
141
Two crosses between the same pair of genotypes or phenotypes in which the sources of the gametes are reversed in one cross, is known as : -
AIPMT 2003
142
Down's syndrome is caused by an extra copy of chromosome number 21. What percentage of offspring produced by an affected mother and a normal father would be affected by this disorder ?
AIPMT 2003
143
Which one of the following conditions though harmful in itself, is also a potential saviour from a mosquito borne infectious disease ?
AIPMT 2003
144
Which one of the following traits of garden pea studied by Mendel was a recessive feature ?
AIPMT 2003
145
There are three genes a, b and c. The percentage of crossing over between a and b is 20%, b and c is 28% and a and c is 8%. What is the sequence of genes on chromosome
AIPMT 2002
146
A gene said to be dominant if : -
AIPMT 2002
147
A diseased man marries a normal woman. They get three daughter and five sons. All the daughter were diseased and sons were normal. The gene of this disease is : -
AIPMT 2002
148
On selfing a plant of F1 generation with genotype “AABbCC”,the genotypic ratio in F2 generation will be
AIPMT 2002
149
Which of the following is a correct match -
AIPMT 2002
150
Which of the following is the example of pleiotropy ?
AIPMT 2002
151
Male XX and female XY sometime occur due to
AIPMT 2001
152
Two nonallelic genes produces the new phenotype when present together but fail to do so independently then it is called : -
AIPMT 2001
153
Ratio of complementry genes is : -
AIPMT 2001
154
When dominant and recessive allels express itself together it is called : -
AIPMT 2001
155
A and B genes are linked. What shall be genotype of progeny in a cross between AB/ab and ab/ab : -
AIPMT 2001
156
Independent assortment of genes does not takes place when : -
AIPMT 2001
157
Number of Barr bodies in XXXX female is
AIPMT 2001
158
Sickle cell anaemia is induce to : -
AIPMT 2001
159
Probability of four son to a couple is : -
AIPMT 2001
160
In Drosophila the XXY condition leads to femaleness whereas in human beings the same condition leads to Klienfelter's syndrome in male. It proves :
AIPMT 2000
161
Erythroblastosis foetalis is caused when :
AIPMT 2000
162
Mongolian idiots are due to trisomy in 21st chromosome is called :
AIPMT 2000
163
Due to the cross between TTRr × ttrr the resultant progenies showed how many percent plants tall, red flowered :
AIPMT 2000
164
According to mendelism which character is showing dominance ?
AIPMT 2000
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