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1
AIPMT 2009
MCQ (Single Correct Answer)
+4
-1
The genetic defect-adenosine deaminase (ADA) deficiency may be cured permanently by
A
Introducing bone marrow cells producing ADA into cells at early embryonic stages
B
Periodic infusion of genetically engineered lymphocytes having functional ADA cDNA
C
Administering adenosine deaminase activators
D
Enzyme replacement therapy
2
AIPMT 2009
MCQ (Single Correct Answer)
+4
-1
Sickle-cell anemia is :
A
Caused by substitute of valine by glutamic acid in the beta globin chain of haemoglobin
B
An autosomal linked dominant trait
C
Caused by a change in a single base pair of DNA
D
Characterized by elongated sickle like RBCs with a nucleus
3
AIPMT 2009
MCQ (Single Correct Answer)
+4
-1
Select the incorrect statement from the following :
A
Baldness is a sex limited trait
B
Galactosemia is an inborn error of metabolism
C
Linkage is an exception to the principle of independent assortment in heredity.
D
Small population size results in random genetic drift in a population
4
AIPMT 2008
MCQ (Single Correct Answer)
+4
-1
Which one of the following conditions in humans is correctly matched with its chromosomal abnormality/linkage?
A
Klinfelter's syndrome — 44 autosomes + XXY
B
Colour-blindness — Y-linked
C
Down syndrome — 44 autosomes + XO
D
Erythroblastosis foetalis — X-linked
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