The slope of the common tangent drawn to the circles $x^2+y^2-4 x+12 y-216=0$ and $x^2+y^2+6 x-12 y+36=0$ is

If $r_1$ and $r_2$ are radii of two circles touching all the four circles $(x \pm r)^2+(y \pm r)^2=r^2$, then $\frac{r_1+r_2}{r}=$

If the equation of the circle having the common chord to the circles $x^2+y^2+x-3 y-10=0$ and $x^2+y^2+2 x-y-20=0$ as its diameter is $x^2+y^2+\alpha x+\beta y+\gamma=0$, then $\alpha+2 \beta+\gamma=$

The locus of the third vertex of a right-angled triangle, the ends of whose hypotenuse are $(1,2)$ and $(4,5)$ is