$p, q$ are two prime numbers. For $n=p q$, if the expansion $\left(\sqrt[4]{x^{-5}}+2 \sqrt[5]{x^5}\right)^n$ contains non-zero coefficient of $x^{-n}$ and $x^0$, then the least value of such $n$ is

The binomial expansion $(7+3 x)^{-2 / 5}$ is valid for all $x$ in the interval $\left(\frac{-7}{3}, \frac{7}{3}\right)$ and if the 4 th term of its expansion is $k x^3$, then $\left(7^{12 / 5} k\right)=$

If ${ }^n C_0,{ }^n C_1,{ }^n C_2, \ldots,{ }^n C_n$ respectively are the binomial coefficients in the expansion of $(1+x)^n$, then when $n=10, \sum_{r=1}^{10}{ }^n C_r \cdot r(r-4)=$

If sum of the coefficients of $x^r(r=0,1,2, \ldots, 2 n)$ in the expansion of $\left(1+3 x-2 x^2\right)^n$ is 128 , then $\sum_{r=1}^{2 n} r \frac{(2 n)_{C_r}}{(2 n)_{C_{r-1}}}=$