Which of the following options represents the given graph?

Which one of the options does NOT describe the passage below or follow from it?

We tend to think of cancer as a 'modern' illness because its metaphors are so modern. It is a disease of overproduction, of sudden growth, a growth that is unstoppable, tipped into the abyss of no control. Modern cell biology encourages us to imagine the cell as a molecular machine. Cancer is that machine unable to quench its initial command (to grow) and thus transform into an indestructible, self-propelled automaton.

[Adapted from The Emperor of All Maladies by Siddhartha Mukherjee]

the digit in the unit's place of the product $$3^{999}\times7^{1000}$$ is __________.

A square with sides of length 6 cm is given. The boundary of the shaded region is defined by two semi-circles whose diameters are the sides of the square, as shown.

The area of the shaded region is _________ cm$$^2$$.