Biomolecules · Chemistry · COMEDK

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MCQ (Single Correct Answer)

1

A small segment of a polypeptide gave on complete hydrolysis 3 molecules of alanine, 2 molecules of glycine and 3 molecules of cysteine. What is the number of peptide linkages in the segment of the polypeptide?

COMEDK 2026 Afternoon Shift
2

Identify the correct statement.

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3

$$ \text { Match the characteristic from Col. I with the Vitamins given in Col. II. } $$

$$
\text { Characteristics }
$$
$$
\text { Vitamins }
$$
A Water soluble that is not excreted easily W $$
\mathrm{B}_2
$$
B Prevents Cheilosis X $$
\mathrm{B}_6
$$
C Fat soluble Y $$
\mathrm{B}_12
$$
D Prevents seizures and convulsions Z E
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4

The secondary structure of protein consists of:

COMEDK 2026 Morning Shift
5

Which of the following is a correct match?

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6

Which among the following is an INCORRECT statement?

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7
Identify the correct statement.
COMEDK 2025 Evening Shift
8

Two statements, one Assertion and the other Reason are given. Choose the right option.

Assertion : Insulin is called a protein whereas Glycyl alanine is not called a protein

Reason : A polypeptide with amino acid residue less than 100 can also be called as a protein if it has a well-defined conformation of a protein.

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9
Which of the following is a water soluble vitamin?
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10

Match A, B, C and D with the appropriate functions given.

Column I Functions
A. Oxidoreductase P. Malfunctioning leads to Addison's disease.
B. Phosphodiester bonds Q. Regulates responses to external stimuli.
C. Adrenal cortex R. Catalyses glycolysis.
D. Epinephrine S. Links nucleotides together.

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11
Which one of the following is the correct statement?
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12
Choose the incorrect statement.
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13

Two statements, one Assertion (A) and the other Reason (R) are given. Choose the correct option.

Assertion: Maltose, a disaccharide, is a reducing sugar and is obtained by the partial hydrolysis of starch in presence of the enzyme diastase.

Reason: Hydrolysis of one mole of Maltose gives one mole each of $\alpha-D-$ Glucose and $\beta-D-$ Fructose.

COMEDK 2025 Morning Shift
14

Match the reactions of Glucose given in Column I with the major product formed in the reaction as in Column II.

Column I - Reactions Column II - Major product
A. $\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6+\mathrm{HI}$ (Heat) P. $\mathrm{HOOC}-(\mathrm{CHOH})_4-\mathrm{COOH}$
B. $\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6+\mathrm{Br}_2(\mathrm{aq})$ Q. $\mathrm{CH}_3-\left(\mathrm{CH}_2\right)_4-\mathrm{CH}_3$
C. $\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6+$ Conc. $\mathrm{HNO}_3$ R. $\mathrm{NH}_4 \mathrm{O}-\mathrm{OC}-(\mathrm{CHOH})_4-\mathrm{CH}_2 \mathrm{OH}$
D. $\mathrm{C}_6 \mathrm{H}_{12} \mathrm{O}_6+2\left[\mathrm{Ag}\left(\mathrm{NH}_3\right)_2\right] \mathrm{OH}$ S. $\mathrm{HOOC}-(\mathrm{CHOH})_4-\mathrm{CH}_2 \mathrm{OH}$

COMEDK 2025 Morning Shift
15

Given are 4 statements related to the chemical properties of Glucose.

Identify the two incorrect statements from the following.

A. It reacts with $$\mathrm{Br}_2$$ (aq) to form Saccharic acid.

B. Reacts with Acetic anhydride to form Glucose tetraacetate.

C. Reacts with Hydroxylamine to give Glucose oxime.

D. It reacts with ammoniacal $$\mathrm{AgNO}_3$$ to form ammonium salt of Gluconic acid with deposition of silver.

COMEDK 2024 Evening Shift
16

Two statements, Assertion and Reason are given. Choose the correct option from the following.

Assertion: In the secondary structure of RNA, double helix structure is formed.

Reason: In the double structure of RNA, two nucleic acid chains are wound about each other and held together by hydrogen bonds between pairs of bases

COMEDK 2024 Evening Shift
17

Match the Vitamins given in Column I with the diseases caused by their deficiency as given in Column II.

Vitamin Deficiency
(A) K (P) Cheilosis
(B) B$$_12$$ (Q) Osteomalacia
(C) B$$_2$$ (R) Permicious Anaemia
(D) D (S) Haemophilia

COMEDK 2024 Evening Shift
18

With reference to vitamins and its deficiency diseases, the correct statements are:

(i) Cheilosis is due to the deficiency of Riboflavin

(ii) The deficiency of Vitamin B6 causes pernicious anaemia

(iii) Osteomalacia is due to the deficiency of Vitamin E

(iv) The deficiency of ascorbic acid causes scurvy

(v) The deficiency of Vitamin A causes xerophthalmia

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19

Among the following peptides, identify the pair where the name and its structure are correctly matched.

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20

Which of the following statement is not true about glucose?

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21

Identify the 2 chemical tests which is not answered by Glucose having an open chain structure

[A] Reaction with Schiff's reagent and with Sodium bisulphite

[B] Reaction with $$\mathrm{HCN}$$ and with $$\mathrm{HI}$$

[C] Reaction with $$\mathrm{HNO}_3$$ and with Acetic anhydride

[D] Reaction with aqueous Bromine and with Hydroxylamine

COMEDK 2024 Morning Shift
22

Match the Hormones listed in Column I with their characteristics listed in Column II

No. Hormone No. Characteristics
A Adrenal Cortex P Mediates responses to external stimuli.
B Epinephrine Q Steroid hormone.
C Estrogen R Iodinated derivative of Tyrosine amino acid.
D Throxine S Its malfunction causes Addison's disease.

COMEDK 2024 Morning Shift
23

Given below are 4 statements about Insulin. Which of these statement/(s) is/are correct?

[A] Insulin is a globular protein consisting of 51 Amino acids.

[B] Insulin is constituted of 3 polypeptide chains linked together.

[C] Insulin is constituted of 2 polypeptide chains linked together by disulphide bonds.

[D] The 3 polypeptide chains in Insulin are linked together by Hydrogen bonding.

COMEDK 2024 Morning Shift
24

Which of the following hexoses will form the same osazone when treated with excess phenyl hydrazine?

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25

Pick out the incorrect statement(s) from the following.

1. Glucose exists in two different crystalline forms, $$\alpha$$-D-glucose and $$\beta$$-D-glucose.

2. $$\alpha$$-D-glucose and $$\beta$$-D-glucose are anomers.

3. $$\alpha$$-D-glucose and $$\beta$$-D-glucose are enantiomers.

4. Cellulose is a straight chain polysaccharide made of only $$\beta$$-D-glucose units.

5. Starch is a mixture of amylase and amylopectin, both contain unbranched chain of $$\alpha$$-D-glucose units.

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26

Which one of the following is an important component of chlorophyll?

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27

One among the 4 Vitamins belonging to $$\mathrm{B}$$ Complex, can be stored in our body. Identify the Vitamin.

COMEDK 2023 Evening Shift
28

Choose the incorrect statement regarding Cellulose.

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29

What is the function platelets?

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30

The monosaccharides of maltose is

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31

The essential amino acids are

(i) Leucine (ii) Glutamic acid (iii) Asparagine (iv) Valine

correct option is

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32

On treatment of glucose with bromine water the product formed is

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33

Which of the following vitamin is responsible for Beri-Beri disease?

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34

Carbon monoxide is poisonous to human beings because

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35

Which one of the following sets of monosaccharides forms sucrose?

COMEDK 2021
36

Which of the following amino acid (NH$$_2$$CHRCOOH) contains polar R group?

COMEDK 2021
37

Among the following enzymes, which one is involved in the given below catalytic reaction?

$${C_6}{H_{12}}{O_6}(aq) \to 2{C_2}{H_5}OH(aq) + 2C{O_2}(g)$$

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38

Xerophthalmia disease causes by which deficiency of vitamin?

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39

The amino acid which is not optically active is

COMEDK 2020