The following pedigree diagram shows the inheritance of a rare genetic disorder (filled shapes depict affected individuals). Which of the following is the most likely pattern of inheritance of the disorder?

In an island with 10,000 individuals, four have sickle cell anemia, a recessive autosomal disease. Assuming that the locus is in Hardy-Weinberg equilibrium, how many individuals in that island are expected to be heterozygous for the disease allele?

The following pedigree chart shows the inheritance of a genetic disorder. I-2 and III-2 are the only affected individuals. Which one of the following is the correct pattern of inheritance of the disorder, and the genotype of the II- 3 individual?

In a given species of flowering plant, the colour of the seeds is exclusively determined by the colour of its seed coat. Seed coat colour in this species is governed by a nuclear gene with two alleles. The WHITE ( $W$ ) allele is dominant over brown ( $w$ ) allele. If a plant with brown seeds $(w w)$ is crossed as a female with pollen from a white seed $(W W)$ plant, what will be the seed colour and the genotype of the embryo in the resultant seeds obtained from this cross?