Principles of Inheritance and Variation · Biology · IAT (IISER)
MCQ (Single Correct Answer)
1
The following pedigree diagram shows the inheritance of a rare genetic disorder (filled shapes depict affected individuals).
Which of the following is the most likely pattern of inheritance of the disorder?

IAT (IISER) 2024
2
In an island with 10,000 individuals, four have sickle cell anemia, a recessive autosomal disease. Assuming that the locus is in Hardy-Weinberg equilibrium, how many individuals in that island are expected to be heterozygous for the disease allele?
IAT (IISER) 2023
3
The following pedigree chart shows the inheritance of a genetic disorder. I-2 and III-2 are the only affected individuals.
Which one of the following is the correct pattern of inheritance of the disorder, and the genotype of the II- 3 individual?

IAT (IISER) 2023
4
A hypothetical plant species shows two flower colour phenotypes- red and white. Red is dominant over white. In a population, this flower colour locus was found to be in HardyWeinberg equilibrium. If 490 out of a total population size of 1000 plants were found to be white-flowered, how many of the red-flowered plants will be heterozygous?
IAT (IISER) 2020